Designer Microbes Expand Life’s Genetic Alphabet

first_imgFrom bacteria to basketball players, all life as we know it encodes genetic information using two pairs of DNA letters. Not anymore. Now, along with the double helix’s two natural pairs—A bound to T and G bound to C—a bacterium growing in a California lab can incorporate and copy a third, artificial pair of letters. For now, the artificial bases—call them X and Y—don’t code for anything, unlike natural DNA base pairs, which in various combinations code for the 20 different amino acids that make up proteins. But the newly expanded genetic code opens the door for synthetic biologists to create microbes capable of building their proteins out of as many as 172 different amino acids, both natural and artificial—a potential boon to drug and materials developers.“This is an amazing enabling technology,” says Ross Thyer, a molecular biologist at the University of Texas, Austin, who was not involved in the work, reported in this week’s issue of Nature. Not only does the feat open the way to a universe of new proteins, but it also gives researchers a new platform for investigating how DNA evolved and why all life is limited to just five bases. (In RNA, T is replaced with U.)Creating synthetic superbacteria might sound ominous. But Eric Kool, a biological chemist at Stanford University in California, says the risks are low. “These organisms cannot survive outside the laboratory,” Kool says. In fact, they can’t even build X and Y (more formally known as d5SICS and dNaM) themselves: Researchers synthesize the bases and feed them to the bacteria. “Personally, I think it’s a less dangerous way to modify DNA” than existing genetic engineering, Kool says.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Over the decades, synthetic biologists trying to expand life’s genetic alphabet have come up with a handful of alternative genetic letters. A few teams, including one led by Floyd Romesberg, a biological chemist at the Scripps Research Institute in San Diego, California, have even managed to get DNA replication proteins called DNA polymerases to copy DNA strands incorporating alternative letters. But that was achieved in test tubes, not inside living cells.Getting live bacteria to replicate altered DNA was another challenge entirely. The bacteria would need either to synthesize the new genetic letters themselves or to import them from the surrounding culture medium. In algae, Romesberg and his colleagues identified a protein that grabs nucleotide bases and pulls them into the cell. They spliced the gene for this transporter protein into Escherichia coli bacteria and found it enabled the bacteria to pull in presynthesized X and Y bases as well. The team had also engineered their E. coli to harbor small rings of DNA called plasmids carrying X-Y pairs. When the bacteria copied those plasmids, they used the newly imported X and Y bases—yet the engineered cells grew just as well as their native cousins.Next, Romesberg says he hopes to use his expanded genetic alphabet to create designer proteins. Scripps biochemist Peter Schultz and others have already engineered bacteria to build proteins with dozens of amino acids beyond nature’s standard 20. But those experiments use natural DNA to code for unnatural amino acids. The newly expanded genetic alphabet, Thyer says, should yield a vastly more diverse menu of proteins with a wide variety of new chemical functions, such as medicines better able to survive in the body and protein-based materials that assemble themselves. Romesberg says forays into that new world of proteins are already under way.last_img read more

Kolkata Derby: Mohun Bagan and East Bengal Play Out Goalless Draw in Calcutta Football League

first_img Get the best of News18 delivered to your inbox – subscribe to News18 Daybreak. Follow on Twitter, Instagram, Facebook, Telegram, TikTok and on YouTube, and stay in the know with what’s happening in the world around you – in real time. Kolkata: East Bengal and Mohun Bagan played a goalless draw in the Kolkata derby in the Calcutta Football League (CFL) Premier Division here on Sunday.Mohun Bagan, who are defending champions of CFL, are eighth in the points table with five points, whereas East Bengal are fourth on the points table with seven points. Kibu Vicuna’s team managed to stop EB’s Alejandro Menendez from getting a hattrick win in Kolkata derbies.Mohun Bagan, undoubtedly, were the superior team with Joseba Beitia brilliantly leading the attack in a 4-4-1-1 formation but V P Suhair let the team down missing a couple of sitters in what was the season’s first Kolkata derby at the Saltlake Stadium.East Bengal midfield looked unorganised especially in the first-half but their defence manned by Marti Crespi did not give any chance to their arch-rivals to come out with a point.East Bengal now have seven points from four matches to occupy fourth place in the table.The defending champions, on the other hand, are languishing in the relegation zone at ninth spot with five points from four outings in the 12-team standings.It is full time at Yuvabharati and the points are shared. #JoyMohunBagan #DreamBigSupportFearlessly— Mohun Bagan (@Mohun_Bagan) September 1, 2019A fortnight ago, Suhair had scored an extra-time brace at the same venue to guide Mohun Bagan to the Durand Cup final but he seemed to have a bad day in office on Sunday.The best chance Suhair got was in the hour’s mark when he found himself at the handshaking distance of East Bengal goal but only to shoot wayward.Then again in the 43rd minute, Suhair surged in with East Bengal defence nowhere in sight as he attempted a grounded shot from inside the box but it went straight to East Bengal goalkeeper Lalthuammawia Ralte.Alexander Romario could have killed the game in the 91st minute after he received a curling cross from Beitia but he failed to find the back of the net.The earliest chance Mohun Bagan got was in the 15th minute when captain Gurjinder Singh’s header from a swinging freekick by Beitia went outside the far-post. A nearly full house witnessed a great game of 90 minutes.#QEBFCvMBAC#AmiLalHolud #QEBFC #QuessEastBengalFC #Kolkata #KolkataFootball #Football #CentenaryYear #IndianFootball #FootballIndia #EastBengalFC #LoveEastBengal #CFL #Derby — Quess East Bengal FC (@eastbengalfc) September 1, 2019It was end-to-end action in the second half with East Bengal pressing the attack but a goal eluded them as well.In the 59th minute, Ralte found himself in the close range but could not connect well with Debjit Majumder out of position.Moments later, Mohun Bagan had their best chance in the first hour’s play but Suhair missed the target just in front of the goal.It was Ashutosh Mehta who gave a fine low cross from the right which needed a simple tap-in but Suhair squandered the sitter.With 20 minutes left on the clock, East Bengal coach Alejandro Menendez brought on his key players, Jaime Santos and Bidyasagar Singh, but they too failed to make any impact.In the second half stoppage time, Mohun Bagan’s Alexander Romario could have scored the winner, with Beitia once again setting it up with a curling cross, but failed to find the back of the net.The last season’s derby saw both teams play out a 2-2 draw while East Bengal won both their legs against their arch-rivals in the I-League.(With inputs from Agencies) calcutta football leaguecfldraweast bengal First Published: September 1, 2019, 5:18 PM ISTlast_img read more

Honda Cars India domestic sales up 22% at 17,085 units in July

first_imgNew Delhi, Aug 1 (PTI) Honda Cars India Ltd (HCIL) today reported a 21.74 per cent increase in its domestic sales at 17,085 units in July.The company had sold 14,033 units in the same month last year, HCIL said in a statement.Last month, the company sold 396 units of small car Brio, 2,971 units of premium hatchback Jazz, 2,913 units of compact sedan Amaze and 4,854 units of mid-sized sedan City.The company also sold 4,894 units of its new compact sports utility vehicle (SUV) WR-V. Besides, SUV BR-V saw sales of 1,042 units. The sales for SUV CR-V stood at 15 units.In addition, it exported a total of 350 units during the month under review.On the sales performance, HCIL President and CEO Yoichiro Ueno said good growth with strong sales numbers was seen across all the models.”We have increased the WR-V supply for our waiting customers from last month and is reflected in the good numbers posted by the model in July,” he added.On the outlook, Ueno said the post-GST price benefits, healthy monsoon and onset of festive season in many regions from August will give another boost to the sales. PTI PRJ BALlast_img read more

Marin with the answer

first_imgMarin scored the winner in the third minute of second half stoppage time to give Olympiacos a 2-1 comeback victory over Asteras Tripolis at the Karaiskakis Stadium. The visitors opened the scoring with Mazza’s penalty in the 26th minute and a TREMENDOUS goal from Fortounis brought Olympiacos level on 54 minutes. The win keeps Olympiacos in control of first place in the standings.Olympiacos began their pressure early on creating multiple opportunities in Asteras’ half in the opening 15 minutes of play. However, it was Asteras Tripolis who took the surprising lead in the 26th minute, when Leali was called for a foul on Mazza in the penalty area, resulting in a spot kick for the visitors. From 11-meters, Mazza made no mistake to give Asteras the 0-1 lead, which stood until halftime. If the Arkades had more composure in front of goal, they could have taken a larger lead into the break.In the opening minutes of the second half, both Cardozo and Viana failed to convert with close ranged headers before Fortounis’ ROCKET from well outside the penalty area brought Olympiacos level on the night. Marko Marin, who has been left out of the roster for many games this season, was subbed on later in the half as Olympiacos pressed on for the winner. In the final ten minutes, Olympiacos pinned Asteras in their penalty area with Donnarumma coming up with big saves to keep the score at 1-1. However, in the third minute of stoppage time, Olympiacos found the breakthrough when Marin brilliantly found de la Bella unmarked in the penalty area and the Spaniard’s shot was well-saved by Donnarumma; the ball then fell to Marin whose rebounded effort found the back of the net, completing the late comeback victory for the Erythrolefki.Marin’s late goal keeps Olympiacos well on track for this year’s Superleague title with yet another comeback victory at the Karaiskaki Stadium. Olympiacos is now 9-points clear of second placed Xanthi and 12-points ahead of third placed Panathinaikos, who play tomorrow against Platanias. Asteras Tripolis are only four points clear of the drop zone, level with Levadiakos on 12 points. This weekend Olympiacos will travel to second placed Xanthi (unbeaten in 11 games) in an anticipated match while Asteras host AEK in Tripoli.Source: (Like us on Facebook, follow us on Instagram, and Twitter)TweetPinShare0 Shareslast_img read more

Watford Signed Greek Goalkeeper Orestis Karnezis

first_imgLONDON (AP) — The Latest on European soccer transfers (all times local):Watford signed Greece goalkeeper Orestis Karnezis on loan from Udinese and Burnley brought in Bermuda striker Nahki Wells on a permanent deal from newly promoted Huddersfield.4:30 p.m.Central midfielder Giannelli Imbula has joined French club Toulouse from Stoke on a season-long deal.The 24-year-old Frenchman failed to shine in the Premier League after joining Stoke for a club-record fee from FC Porto two seasons ago.Prior to joining Porto, Imbula had a good spell with Marseille for two seasons, playing 66 games in the French league.___3:10 p.m.Liverpool striker Divock Origi has joined German team Wolfsburg on a season-long loan deal.The Belgium international was set to be the fourth-choice striker at the Premier League club this season, behind Roberto Firmino, Daniel Sturridge and Dominic Solanki.Origi was signed from Lille in 2014 and spent a season back on loan at the French club before scoring 21 goals in 77 appearances for Liverpool over two years. He was never a regular starter, though.___2:05 p.m.Portugal winger Renato Sanches has joined Swansea on season-long loan from Bayern Munich in one of the most improbable signings in Europe’s transfer window.Sanches won the Young Player of the Tournament award at the European Championship last year after helping Portugal win its first major soccer title. Weeks earlier, he had joined Bayern on one of the richest contracts in Bundesliga history for a transfer fee that could climb to about $90 million.The dreadlocked winger was being talked up as the natural heir to Cristiano Ronaldo in Portugal’s national team, but he wasn’t a regular for Bayern last season.Swansea manager Paul Clement likely played a big role in the move for the 20-year-old Sanches, having been assistant coach at Bayern during the first half of last season.___12:50 p.m.Ivory Coast right back Serge Aurier has completed his move to Tottenham from Paris Saint-Germain.The transfer was held up because there were complications with Aurier securing a work permit because he was sentenced to two months in prison last year for resisting arrest after leaving a Paris nightclub.Aurier appealed against the sentence and never went to prison. PSG had to leave him out of its Champions League squad for a match against Arsenal in London last season because he was refused entry because of the ongoing case.The 24-year-old Aurier played 57 league games for PSG, scoring twice, after joining from Toulouse, initially on loan in 2014. He won two league titles, three French Cups and three League Cups.___12:05 p.m.Alex Oxlade-Chamberlain has left Arsenal after six years to join Premier League rival Liverpool for an initial fee of 35 million pounds ($45 million).The 24-year-old Oxlade-Chamberlain allowed his Arsenal contract to enter its final season after rejecting offers of a new deal, and had been linked with a move across London to Chelsea.Facing the prospect of losing Oxlade-Chamberlain on a free transfer next year, Arsenal decided to cash in and Liverpool announced his transfer on Thursday on a “long-term” deal.___7:30 a.m.Algeria says it has given winger Riyad Mahrez permission to leave the national squad to “formalize his transfer to his new club.”Mahrez handed in a transfer request at Leicester days after the end of last season. Leicester rejected bids from Italian team Roma over the offseason. Mahrez, English soccer’s player of the year in the 2015-16 season, has played in Leicester’s first three games of the Premier League.Mahrez was with Algeria ahead of games against Zambia.___6 a.m.It’s the final day for soccer teams in England, France, Germany and Italy to sign players this year.After Thursday, the next chance they will have to strengthen their squads is in January.The transfer window closes on Thursday at 1600 GMT in Germany, and at 2200 GMT in England, France and Italy.Spanish clubs have an extra day to complete player recruitment, with the transfer deadline not until 2200 GMT Friday.TweetPinShare0 Shareslast_img read more

Southampton Test: Kohli and Rahane heroics not enough, India lose series to England

first_imgVirat Kohli and Ajinkya Rahane’s gritty knocks on Day 4 went in vain as India lost the fourth Test by 60 runs against England in Southampton on Sunday. England now have an unbeatable 3-1 lead in the five-match series.This is the third successive Test series loss for India in England after 2011 and 2014.England had set India a target of 245 after getting bowled out for 271 in their second innings early on day 4.India in reply, got off to a poor start as KL Rahul, Cheteshwar Pujara and Shikhar Dhawan departed in quick succession to leave the team reeling at 22 for 3 in the first session.India vs England 4th Test Day 4: HighlightsCaptain Kohli and vice-captain Rahane then started the rebuilding process for India and steadied the innings with a dogged 101-run partnership off 254 balls for the fourth wicket.But India’s innings fell apart once Kohli fell for 58 to Moeen Ali at the stroke of tea.For more than two hours in the second session, Kohli and Rahane were in control. But Kohli perished after registering his 19th half-century in Tests. A delivery from Moeen got a sharp bounce to kiss Kohli’s gloves and Alaistair Cook took an easy catch at short leg in a big relief for the hosts.Hardik Pandya was sent back to the pavilion by Ben Stokes soon after. Rishabh Pant then came out all guns blazing but his cameo didn’t last long as he departed for a 12-ball 18.Virat Kohli first Indian to score 4000 runs as Test captainadvertisementRahane then fell in the final session which was really the final nail in the coffin for India.Ravichandran Ashwin blazed away for a spirited 25 to keep England waiting before Sam Curran finished it off by trapping him lbw as India’s innings folded for 184.England win the 4th Test by 60 runs and take an unassailable lead of 3-1 in the five match Test series.#ENGvIND (@BCCI) September 2, 2018Rahane made 51 runs but the rest of the batsmen once again failed to live up to the expectations with Rahul, Hardik Pandya and Ishant Sharma failing to trouble the scorers.Off-spinner Moeen was once again the pick of the bowlers for England on a slow and dry fourth-day pitch at the Rose Bowl. Moeen followed up his five-wicket haul in the first innings with four wickets for 71 runs in the second.Moeen got excellent support from Ben Stokes and James Anderson, who managed to bag 2 wickets each while Stuart Broad and Sam Curran got one wicket each.Earlier, India bowled out England for 271 in their second innings, early on day 4, with Mohammed Shami finishing with 4 wickets while Ishant Sharma got two. England had conceded a 27-run first-innings lead to India after posting 246 runs batting first on day 1. In reply, India made 273 runs in their first innings with Pujara remaining unbeaten on 132.The two teams will meet again for the fifth and final Test which will be played at The Oval in London from September 7.last_img read more

Millennials more likely to attend Remembrance Day ceremonies poll

first_imgA new survey suggests millennials are leading a gradual resurgence of interest when it comes to attending Remembrance Day ceremonies.The poll conducted by Ipsos on behalf of Historica Canada found that 29 per cent of respondents plan to attend a ceremony to honour fallen soldiers on Nov. 11, up three per cent from last year and marking a return to recent highs established in 2015.But the online survey suggests Canadians between 18 and 34 are the ones most likely to pay their respects in person.The poll found 37 per cent of millennial respondents planned to attend a ceremony, well ahead of the 29 per cent of baby boomers over age 55 who were surveyed.Just 23 per cent of survey participants aged between 35 and 54, classed as members of generation X, expressed an intention of going to an official ceremony.Historica Canada says the surge in interest in attending Remembrance Day ceremonies may be the result of increased efforts to share veterans’ stories in schools and other public spaces, exposing younger generations to real-life accounts of time in combatcalast_img read more

AMC Grand Chief Nepinak discusses First Nation education battle

first_imgAPTN National NewsThere’s a new twist on the fate of the First Nation Control of First Nation Education Act.A hearing scheduled this week for a Federal Court judicial review of the Act launched by the Assembly of First Nations in Quebec and Labrador was postponed following the surfacing of a document signed by the former national chief of the AFN Shawn Atleo.Assembly of Manitoba Chiefs Grand Chief Derek Nepinak discusses the issue with APTN.last_img

Middle East attack jolts oilimport dependent Asia

SEOUL, Korea, Republic Of — The blasts detonated far from the bustling megacities of Asia, but the attack this week on two tankers in the strategic Strait of Hormuz hits at the heart of this region’s oil-import-dependent economies.While the violence only directly jolted two countries in the region — one of the targeted ships was operated by a Tokyo-based company; a nearby South Korean-operated vessel helped rescue sailors — it will unnerve major economies throughout Asia.Officials, analysts and media commentators on Friday hammered home the importance of the Strait of Hormuz for Asia, calling it a crucial lifeline, and there was deep interest in for more details about the still sketchy attack and in what the United States and Iran would do in the aftermath.In the end, whether Asia shrugs it off, as some analysts predict, or its economies shudder as a result, the attack highlights the widespread worries here over an extreme reliance on a single strip of water for the oil that fuels much of the region’s shared progress.Here is a look at how Asia is handling rising tensions in a faraway but economically crucial area, compiled by AP reporters from around the world:___WHY ASIA WORRIESThe oil, of course.Japan, South Korea and China don’t have enough of it; the Middle East does, and much of it flows through the narrow Strait of Hormuz.This could make Asia vulnerable to supply disruptions from U.S.-Iran tensions or violence in the strait.The attack comes months after Iran threatened to shut down the strait to retaliate against U.S. economic sanctions, which tightened in April when the Trump administration decided to end sanctions exemptions for the five biggest importers of Iranian oil, which included China and U.S. allies South Korea and Japan.Japan is the world’s fourth-largest consumer of oil — after the United States, China and India — and relies on the Middle East for 80 per cent of its crude oil supply. The 2011 Fukushima nuclear disaster led to a dramatic reduction in nuclear power generation and increased imports of natural gas, crude oil, fuel oil and coal.In an effort to comply with Washington, Japan says it no longer imports oil from Iran. Officials also say Japanese oil companies are abiding by the embargo because they don’t want to be sanctioned. But Japan still gets oil from other Middle East nations using the Strait of Hormuz for transport.South Korea, the world’s fifth largest importer of crude oil, also depends on the Middle East for the vast majority of its supplies.Last month, South Korea halted its Iranian oil imports as its waivers from U.S. sanctions on Teheran expired, and it has reportedly tried to increase oil imports from other countries like Qatar and the United States.China, the world’s largest importer of Iranian oil, “understands its growth model is vulnerable to a lack of energy sovereignty,” according to market analyst Kyle Rodda of IG, an online trading provider, and has been working over the last several years to diversify its suppliers. That includes looking to Southeast Asia and, increasingly, some oil-producing nations in Africa.___THE GEOGRAPHY AND THE POLITICSAsia and the Middle East are linked by a flow of oil, much of it coming by sea and dependent on the Strait of Hormuz, which is the passage between the Persian Gulf and the Gulf of Oman.In April, Iran threatened to close the strait. Iran also appears poised to break a 2015 nuclear deal with world powers, an accord that U.S. President Donald Trump withdrew from last year. The deal saw Tehran agree to limit its enrichment of uranium in exchange for the lifting of crippling sanctions.For both Japan and South Korea, there is extreme political unease to go along with the economic worries stirred by the violence in the strait.Both nations want to nurture their relationship with Washington, a major trading partner and military protector. But they also need to keep their economies humming, which requires an easing of tension between Washington and Tehran.Japan’s conservative prime minister, Shinzo Abe, was in Tehran, looking to do just that, when the attack happened.His limitations in settling the simmering animosity, however, were highlighted by both the timing of the attack and a comment by Iranian Supreme Leader Ayatollah Ali Khamenei, who told Abe that he had nothing to say to Trump.In Japan, the world’s third largest economy, the tanker attack was front-page news.The Nikkei newspaper, Japan’s major business daily, said that if mines are planted in the Strait of Hormuz, “the oil trade will be paralyzed.” The Tokyo Shimbun newspaper called the Strait of Hormuz Japan’s “lifeline.”Although the Japanese economy and industry minister has said there will be no immediate effect on the stable energy supply, the Tokyo Shimbun noted “a possibility that Japanese people’s lives will be affected.”South Korea, worried about Middle East instability, has worked to diversify its crude sources since the energy crises of the 1970s and 1980s.___THE FUTUREAnalysts said that it’s highly unlikely that Iran would follow through on its threat to close the strait. That’s because a closure could also disrupt Iran’s own exports to China, which has been working with Russia to build pipelines and other infrastructure that would transport oil and gas into China.For Japan, the attack in the Strait of Hormuz does not represent an imminent threat to Tokyo’s oil supply, said Paul Sheldon, chief geopolitical adviser at S&P Global Platts Analytics.“Our sense is that it’s not a crisis yet,” he said of the tensions.Seoul, meanwhile, will likely be able to withstand a modest jump in oil prices unless there’s a full-blown military confrontation, Seo Sang-young, an analyst from Seoul-based Kiwoom Securities, said.“The rise in crude prices could hurt areas like the airlines, chemicals and shipping, but it could also actually benefit some businesses, such as energy companies (including refineries) that produce and export fuel products like gasoline,” said Seo, pointing to the diversity of South Korea’s industrial lineup. South Korea’s shipbuilding industry could also benefit as the rise in oil prices could further boost the growing demand for liquefied natural gas, or LNG, which means more orders for giant tankers that transport such gas.___AP writers Yuri Kageyama in Tokyo, Kim Tong-hyung and Hyung-jin Kim in Seoul, Yanan Wang in Beijing, Annabelle Liang in Singapore and Alexandra Olson in Washington contributed to this report.Foster Klug, The Associated Press read more

American Sniper shoots down Super Bowl weekend boxoffice record with 319 million

AddThis Sharing ButtonsShare to TwitterTwitterShare to FacebookFacebookShare to RedditRedditShare to 電子郵件Email NEW YORK, N.Y. – “American Sniper” shot down another box-office record: Its $31.9 million is the biggest Super Bowl weekend gross ever.According to studio estimates Sunday, the Clint Eastwood film narrowly surpassed the previous top Super Bowl weekend draw. The concert film “Hannah Montana/Miley Cyrus: The Best of Both Worlds Concert Tour” earned $31.1 million in 2008.Hollywood often avoids competing with the Super Bowl as movie-going falls dramatically on Sunday, but “American Sniper” has proven an unlikely sensation. It has now made $248.9 million in six weeks (and only three weeks of wide release), making it the most lucrative war movie without adjusting for inflation. (The distinction was previously held by Steven Spielberg’s “Saving Private Ryan.”)The competition was thin, as Hollywood held off any high-profile releases, largely ceding the weekend to football.The Weinstein Co. animated adaptation “Paddington” came in a distant second with $8.5 million in its third weekend. In a virtual tie with it was Paramount’s found-footage, time-travelling thriller “Project Almanac.”Made by Michael Bay’s production company, Platinum Dunes, “Project Almanac” led a trio of new releases with modest box-office ambitions.“Black or White,” a racially-charged custody drama that reteams Kevin Costner with “The Upside of Anger” director Mike Binder, opened in fourth with $6.5 million. Costner put up his own money to help finance the film, which Relativity Media distributed.Open Road’s “The Loft,” a much-delayed remake of a 2008 Dutch thriller directed by its original filmmaker, Erik Van Looy, attracted little interest. It made just $2.9 million.That wasn’t much more than the $1.5 million pulled in by a package of TV reruns. The HBO series “Game of Thrones” earned that in 205 Imax theatres by showing previously aired episodes ahead of the April debut of the show’s fifth season.Estimated ticket sales for Friday through Sunday at U.S. and Canadian theatres, according to Rentrak. Where available, the latest international numbers for Friday through Sunday are also included. Final domestic figures will be released Monday.1. “American Sniper,” $31.9 million.2. “Paddington,” $8.5 million.3. “Project Almanac,” $8.5 million.4. “Black or White,” $6.5 million.5. “The Boy Next Door,” $6.1 million.6. “The Wedding Ringer,” $5.7 million.7. “The Imitation Game,” $5.2 million.8. “Taken 3,” $3.7 million.9. “Strange Magic,” $3.4 million.10. “The Loft,” $2.9 million.___Universal and Focus are owned by NBC Universal, a unit of Comcast Corp.; Sony, Columbia, Sony Screen Gems and Sony Pictures Classics are units of Sony Corp.; Paramount is owned by Viacom Inc.; Disney, Pixar and Marvel are owned by The Walt Disney Co.; Miramax is owned by Filmyard Holdings LLC; 20th Century Fox and Fox Searchlight are owned by 21st Century Fox; Warner Bros. and New Line are units of Time Warner Inc.; MGM is owned by a group of former creditors including Highland Capital, Anchorage Advisors and Carl Icahn; Lionsgate is owned by Lions Gate Entertainment Corp.; IFC is owned by AMC Networks Inc.; Rogue is owned by Relativity Media LLC.___Follow AP Film Writer Jake Coyle on Twitter at: ‘American Sniper’ shoots down Super Bowl weekend box-office record with $31.9 million by Jake Coyle, The Associated Press Posted Feb 1, 2015 9:52 am MDT This photo released by Relativity Media shows Octavia Spencer and Anthony Mackie, right, in a scene from Relativity Media’s “Black or White.” (AP Photo/Relativity Media, Tracy Bennett) read more

Success of Indigenous Peoples World Conference integral to humanitys progress – Ban

“The success of this Conference is integral to progress for all humanity,” Mr. Ban said today as he opened the World Conference at UN Headquarters alongside General Assembly President Sam Kutesa, and UN High Commissioner for Human Rights, Zeid Ra’ad Al Hussein.Convened as a first high-level plenary meeting of the General Assembly’s 69h session, the two-day World Conference brings together over a thousand indigenous and non-indigenous delegates to discuss the realization of their rights, including pursuing the objectives of the UN Declaration on the Rights of Indigenous Peoples, adopted by the Assembly in 2007.“Indigenous peoples are concerned about issues that top the global agenda. They are deeply connected to Mother Earth- whose future is at the heart of the Climate Summit opening tomorrow,” said Mr. Ban. He recalled meeting with indigenous leaders in Costa Rica, where they shared with him their worries about land, resources and their rights. And just last month in New Zealand, Mr. Ban said he spent a day in Tuapo with Maori leaders where he was impressed by their multimillion dollar horticulture, waste management and energy production companies. “I will never forget how every bit of waste is fed to worms that create very rich organic fertilizer. This is sustainability in action. It showed how much the world can learn from indigenous peoples,” Mr. Ban said. Today’s Outcome Document – an action-oriented text on implementing the rights of indigenous peoples – must bridge the gap between promises and results, he said of the measure, adopted during the Conference’s opening ceremony. Echoing that sentiment, General Assembly President Kutesa said more could be done at the national level to improve the conditions of indigenous peoples as there continues to be a “deep chasm” on the ground between commitments and reality.“This will require Member States to make greater efforts to translate this Outcome Document into reality and demonstrate resolve in addressing inequalities that adversely affect indigenous communities,” Mr. Kutesa added. The UN indigenous Peoples’ Declaration represents a global consensus and has galvanizes international attention of the rights of indigenous peoples, but today’s gathering takes it further. “The process leading to this Conference has been unprecedented in the history of the Organization, as it has involved active participation of indigenous peoples in its preparation, as well as cooperation between Member States and indigenous peoples in the preparation of the Outcome document,” said Mr. Kutesa.Also addressing the Assembly today was Ms. Dalee Sambo Sorough, Chair of UN Permanent Forum on Indigenous Issues, who said long after the Conference ends, the spirit of partnership must continue to thrive at the regional and national levels, but perhaps most importantly, at the local level among indigenous peoples themselves.Only this “spirit of solidarity” will provide support needed to implement the Outcome Document.Ms. Sorough called on UN Member States to be guided not only by legal imperatives and international obligations but also by moral imperatives and moral obligations.“Indigenous peoples’ right to their land and resources remains essential to their survival,” Ms. Sorough said, adding that good governance cannot become a casualty when a few states or even one State undermine principles of equality and democracy. Indigenous peoples represent remarkable diversity – more than 5,000 distinct groups in some 90 countries, making up more than 5 per cent of the world’s population, some 370 million people. These peoples continue to self-identify as distinct peoples with strong links to traditional territories with their own social, economic and political systems as well as unique languages, cultures and beliefs. read more

Buckeye Brief Urban Meyers thoughts on Ohio States Early Signing Day

Ohio State coach Urban Meyer observes the field at Memorial Stadium prior to the Buckeyes’ season-opening 49-21 win over Indiana on Aug. 31 in Bloomington, Indiana. Credit: Colin Hass-Hill | Sports EditorA year ago at this time, no players had signed letters of intent to play football for Ohio State. But this year, the first in which the Early Signing Period was introduced, the Buckeyes inked the signatures of 21 players in its 2018 recruiting class, which, despite recent key decommitments, is currently ranked No. 1 by 247Sports.Wednesday morning, just a few hours after Ohio State received its first letter of intent — which came from four-star linebacker Teradja Mitchell — head coach Urban Meyer spoke to the media about the latest recruiting class. Here are four takeaways from the press conference.Update on Micah ParsonsFive-star defensive end Micah Parsons signed a letter of intent with Penn State Monday morning after a tumultuous recruiting cycle that included a decommitment from the Nittany Lions. A couple months ago, Ohio State looked like a favorite to land his commitment, but the Buckeyes interest faded for an unknown reason as time passed.On Tuesday, The Lantern reported Ohio State self-reported NCAA violations stemming from the Parsons family’s visit to the set of College GameDay. The university self-imposed punishments, which included an agreement to end the recruitment of Parsons, who the program deemed ineligible. “Everybody in our program should know the rules, and that shouldn’t have happened,” Meyer said. “It’s presented to me, and I agree with it or disagree with it, and we move on.”Even if a violation sounds minor, Meyer said he does not believe it to be minor.“I get extremely upset when I see that there was something done that was done incorrectly, and we do everything we possibly can to make sure that does not happen again,” he said. Meyer declined to comment on whether the violation was the reason Ohio State ended its recruitment of Parsons.Ohio State found its quarterback. Eventually. Since July 29, 2016, Ohio State held a commitment from Emory Jones, the fourth-ranked dual-threat quarterback, according to 247Sports composite rankings. But on Early Signing Day, he flipped to Florida and signed with the Gators. The Buckeyes, though, were prepared for what seemed like the inevitable after Jones took visits to Florida, Florida State and Alabama as Wednesday’s signing day neared. On Dec. 7, Ohio State received a pledge from three-star quarterback Matthew Baldwin, a former Colorado State commit.Baldwin, a first-year starter at Lake Travis High School in Texas, was brought to the attention of Meyer by quarterbacks coach and co-offensive coordinator Ryan Day.“We’re sitting there getting ready to play Penn State, and he’s coming up to me saying, ‘Hey, let’s watch this kid from Lake Travis,’” Meyer said. “And I’m ready to pass out, saying it’s 10:30 at night, I’ve got 3rd down and 6 in my mind and we’re trying to watch another quarterback.”Meyer went to watch Baldwin practice and liked what he saw. The head coach said he evaluates five traits in quarterbacks: competitive spirit, toughness, leadership, intelligence and the ability to get out of a bad play.“I think you see so many mistakes made at that position because people don’t categorize like that, and he checks the box off perfectly going right down the list,” Meyer said.Jeremy Ruckert: best tight end prospect Meyer has seen?Since Meyer arrived in Columbus in 2012, Ohio State has coached tight ends Jeff Heuerman and Nick Vannett, both future third-round picks in the NFL draft, and landed commitments from four-star tight ends such as Marcus Baugh, Jake Hausmann and Luke Farrell.But he thinks four-star tight end Jeremy Ruckert is different.“I think Jeremy Ruckert might be the best tight end prospect that I’ve ever seen and recruited,” Meyer said. “His skill set is ridiculous. Now it’s a question of getting him ready to play.”Ruckert, the top-ranked player from his home state of New York, is the best tight end and the No. 29 overall player in the nation, according to the 247 composite rankings. Given his athleticism, the 6-foot-6, 240-pound physical specimen could be viewed as more of a receiver at times. He will offer Ohio State a receiving threat from the tight end position to which the program has not been accustomed. Baugh, the Buckeyes’ starting tight end, ranks fourth on the team with 24 catches this year. Next season, Ruckert will compete with Hausmann, Farrell and redshirt sophomore Rashod Berry for the starting tight end position following Baugh’s departure.Late addition of Alex WilliamsAs Ohio State’s recruiting strategy has a more national focus, the Buckeyes have moved away from in-state recruiting. But on Wednesday, Ohio State flipped Pickerington, Ohio, product Alex Williams from West Virginia to the Scarlet and Gray.The three-star athlete who plays for Pickerington North is ranked the 589th-best player in the country and the No. 26 player in Ohio by the 247Sports composite rankings. He is listed as a defensive end by recruiting services, but Meyer said he intends to try him at both tight end and defensive end.“Big athlete,” Meyer said. “I think he can do either. I know where — there’s needs at both spots, but I don’t know.”Meyer said his decision to pursue Williams was partially due to his desire for more players from Ohio. He and the recruiting staff often look for in-state late bloomers because he does not feel like the team has enough Ohioans.“I started watching him, and he’s a late developer player that I think he was hurt some of his junior year, and I like the fact he plays extremely hard and he’s a big athlete.” read more

Facebook rachète la startup Tagtile

first_imgFacebook rachète la start-up TagtileUne semaine après l’annonce du rachat d’Instagram, Facebook s’offre une nouvelle société. La firme de Mark Zuckerberg a acquis la start-up Tagtile, jeune pousse spécialisée dans la gestion de la relation et la fidélisation des clients mobile.Quelques jours seulement après avoir acquis pour un milliard de dollars l’application de partage de photos pour smartphones Instagram, Facebook poursuit ses rachats en vue de sa prochaine  entrée en bourse. Le réseau social aux 845 millions de membres vient ainsi de s’offrir la jeune société californienne Tagtile. À lire aussiDengue : symptômes, traitement, prévention, où en est-on ?Cette start-up fondée il y a à peine plus d’un an développe et édite un système de gestion de la relation client, qui vise àfidéliser les utilisateurs de smartphones via des bons de réduction et diverses promotions offerts par de nombreuses boutiques en ligne pour les remercier de leurs achats. Ces récompenses sont réunies au sein d’une seule et unique application disponible sur Android comme sur iOS.Tagtile annonce la nouvelle dans un communiqué (lien non disponible), mais ne précise pas le montant de son rachat par Facebook. La start-up se contente de se réjouir, en affirmant que “cette opération constitue une énorme opportunité de réaliser (son) objectif  – aider les entreprises à se développer – en le portant à grande échelle”.Le 16 avril 2012 à 21:00 • Maxime Lambertlast_img read more

Men help save basketball teammates life with first aid

first_imgBATTLE GROUND — As they walked off the court April 24, Jeremy Browning joked with George Tierney, who’s many years his senior, about how Browning’s getting too old for basketball.“I say, ‘Crap, George, I’m not going to play, my knees are getting that bad,’” Browning said Monday between games at Chief Umtuch Middle School in Battle Ground.They had just finished a game of basketball in their 35-and-older community league, which plays at the school.“All I did was turn around,” Browning said, then thud. Tierney, 69, had fallen.The members of the Over the Hill league sprang to action. They checked his vitals, started chest compressions, called 911 and grabbed one of the school’s automated external defibrillators. Their efforts helped save Tierney’s life.Clark County Fire District 3 honored the group at a Wednesday evening gathering at Chief Umtuch Middle School.Between jokes about how a league with a name like Over the Hill seemed a bit broad for a 35-and-older league, school and fire district officials lauded the team’s actions.Fire District Chief Steve Wrightson said the team’s help meant paramedics arrived to the best situation they could hope for.“We had CPR-trained people, we had people willing to jump in and help — that doesn’t always happen,” Wrightson said. “And a facility that is prepared with the right equipment.”last_img read more

SimpsonMiller resigns PNP Leadership

first_imgFacebook Twitter Google+LinkedInPinterestWhatsApp Recommended for you ALERT # 2 ON POTENTIAL TROPICAL CYCLONE NINE ISSUED BY THE BAHAMAS DEPARTMENT OF METEOROLOGY THURSDAY 12TH SEPTEMBER, 2019 AT 9 PM EDT Electricity Cost of Service Study among the big agenda items at September 11 Cabinet meeting Related Items:#magneticmedianews Facebook Twitter Google+LinkedInPinterestWhatsAppJamaica, February 7, 2017 – Jamaica’s Portia Simpson Miller will resign as Opposition Leader of business in the House of Assembly for the People’s National Party.  Madame Miller, a two time Prime Minister of Jamaica demits her party’s office on April 2, 2017 but will remain active as the MP for St Andrew South West.#MagneticMediaNews The Luxury of Grace Bay in Down Town Provolast_img read more

3rd annual CODEchella competition

first_img Posted: May 18, 2018 00:00 00:00 spaceplay / pause qunload | stop ffullscreenshift + ←→slower / faster ↑↓volume mmute ←→seek  . seek to previous 12… 6 seek to 10%, 20% … 60% XColor SettingsAaAaAaAaTextBackgroundOpacity SettingsTextOpaqueSemi-TransparentBackgroundSemi-TransparentOpaqueTransparentFont SettingsSize||TypeSerif MonospaceSerifSans Serif MonospaceSans SerifCasualCursiveSmallCapsResetSave SettingsSome of San Diego’s youngest and brightest minds met at San Diego City College for the 3rd annual “CODEchella.”It’s an event where students go head-to-head in challenges where they program “spheros” and drones.They also got to share their projects with other participants.Over 100 middle and high school student competed in the coding event.Aside from having fun, it’s all about preparing these young adults for the future of San Diego.The competition has recently grown to include students of all levels of experience. KUSI Newsroom 3rd annual ‘CODEchella’ competition KUSI Newsroom, May 18, 2018 Categories: Local San Diego News FacebookTwitterlast_img read more

Post Office staff to strike in pensions dispute

first_imgPost Office managers who are members of trade union Unite and employees who are members of the Communication Workers Union (CWU) will undertake 24-hour strike action on Saturday 3 December 2016 in a ongoing dispute over pensions.Around 720 Post Office managers will join CWU members in targeting 300 Crown Office branches for industrial action in a dispute over the proposed closure of the organisation’s defined benefit (DB) pension scheme and the franchising of Crown Offices.The proposed closure of the DB scheme would take place in April 2017. It is expected to affect approximately 3,500 employees. A defined contribution (DC) pension scheme is already in place for other Post Office employees.Unite’s members voted 64% in favour of strike action, with 78% supporting industrial action short of a strike. The Post Office managers have already undertaken two 24-hour strikes on 15 September and 31 October 2016.Brian Scott, officer for the Post Office at Unite, said: “We are taking this action because the management refuses to talk in a constructive manner about the pension scheme which is currently in surplus to more than £143 million.“This is the retirement income of our members which is at stake and we are not going to stand idly by and let them lose thousands of pounds when they retire.”A Post Office spokesperson said: “We are frustrated that our unions have called for further strike action. We want to reach a constructive way forward through talks, and have been inviting them to meet with our group executive to discuss our strategy in detail since April this year. Our latest invitation to meet them in December remains unanswered. “The changes being made across our directly managed [Crown] network are to safeguard our services at the heart of high streets and city centres for future generations. We must respond to changing customer needs.“Protecting the benefits built up in the [DB pension plan] and keeping it properly funded is the right and responsible thing to do for members of the plan.”Dave Ward, general secretary at CWU, said: “The Post Office is now at crisis point; it needs a new strategy as a matter of urgency. No-one is thinking of the future. This isn’t good for [employees], it isn’t good for customers and it isn’t good for the future of the business. “The CWU will not simply stand by and see another British industry destroyed. We have a simple demand; that the government pauses the cuts and brings stakeholders together for a structured period of talks to develop a plan that is about more than managing the decline of the service. Our members and the public deserve nothing less.”last_img read more

Work shop on Anandha Vedika

first_imgKadapa: As part of initiative in promoting qualitative education to students in government schools in an easy and interesting manner the education department has organized one day work shop for teaching in the name of Anandhavedika ((Happiness curriculum)at ZP school in Patha kadapa here on Tuesday. Speaking the occasion writer of Anandha Vedika Text book and also state resource person S.Rahamtullah said that the aim of conducting work shop is in order to sensitize the teaching staff over importance and implementation of programme in the interest of student community. He said Anandha Vedika Text Book conspiring important items like story telling, Activities, Expressions, promoting confidence, concentration, and positive attitude among the children. He said that this text book will be introduce in all government schools on 4th July across the state.last_img read more

MoD blacklists Swiss firm Pilatus as CBI probes dubious 2012 aircraft deal

first_img Close The ban by MoD has further complicated matters for Pilatus, which is already under scrutiny at home. Switzerland’s office of the attorney general has opened a criminal investigation in connection with the sale of military training aircraft to Saudi Arabia and the United Arab Emirates. However, the allegations were not specified the investigations were linked to alleged violations of Swiss law governing private security services. IBTimes VideoRelated VideosMore videos Play VideoPauseMute0:01/1:11Loaded: 0%0:01Progress: 0%Stream TypeLIVE-1:10?Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedSubtitlessubtitles settings, opens subtitles settings dialogsubtitles off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window. COPY LINKAD Loading … Indian Air Force inducts Boeing Chinook helicopters PC-7 Mk IIpilatus-aircraft.comThe embattled Swiss aerospace manufacturer, Pilatus, has been banned by the Ministry of Defence (MoD) for one year. The ban came in the backdrop of the Central Bureau of Investigation (CBI) registering cases against Pilatus for allegedly bagging Rs 2,800 crore deal in 2012.Last week, the Indian Airforce (IAF) abandoned its plan of buying 38 more Pilatus PC-7 MkII planes from Switzerland. The IAF will now go for a fresh tender for basic trainers. The cancellation of the plan is further expected to delay the induction of much-needed basic trainer aircraft.The ban on Pilatus will force the IAF to find options to source spares and parts for its existing fleet of the basic trainers. The IAF is currently operating 75 Pilatus PC 7 Mk1 aircraft.The official notification of MoD read: “Business dealings with the firm will remain suspended for a period of one year for violation of article 6.6 of the PCIP (Pre Contract Integrity Pact) and ongoing investigation by CBI, Delhi Police, ED and Income Tax Department into corrupt practices, unfair means and illegal activities by Pilatus Aircraft Limited.” IAF Pilots alongside Pilatus during its induction in 2013Credit: ReutersMoD is acting tough on corruption charges against Pilatus and its partners in India. Last month, the ministry banned fugitive arms dealer Sanjay Bhandari who played a major role in brokering the deal for Pilatus. Bhandari is now being investigated by Indian agencies and declared absconding.The Economic Times reported that MoD had sent a show-cause notice to Pilatus in 2017. The company admitted that they engaged with Bhandari’s company Offsets India Solutions (OIS) and paid least 1 million Swiss francs in 2010. The payments were made for trainer jet for IAF.last_img read more

Report Reinforces Role Of Texas In Wind Energy

first_img Listen 00:00 /13:50 Share In 2018, amid record demand, U.S. wind energy providers increased their capacity by 8 percent.That’s according to new analysis from the American Wind Energy Association, which released its U.S Wind Industry Annual Market Report today at the Greater Houston Partnership.The organization says Texas is home to about a quarter of all wind power capacity in the country, with the ability to generate some 25,000 megawatts. The industry employs just as many Texans as well. Still, renewable power remains heavily subsidized in the state.In the audio above, John Hensley, vice president of research and analytics for AWEA, joins Houston Matters to update us on how the wind energy industry in Texas changed in 2018, what keeps the wind industry growing in the Lone State State, and how that compares to national trends.center_img To embed this piece of audio in your site, please use this code: Xlast_img read more